Semi-synthetic ecteinascidins .
Publication number: EP1876180
Publication date: 2008-01-09
Inventor: RINEHART KENNETH LLOYD (US); MORALES JOSE J (US)
Applicant: TRUSTEES OF THE UNIVERSITY OF (US)
Classification:
- international: C07D497/22; C07D515/22; A61K31/47; A61K31/495; A61K31/4995; A61K31/50; A61K35/56; A61P35/00; A61P35/02; C07D519/00; C07D497/00; C07D515/00; A61K31/47; A61K31/495; A61K31/4995; A61K31/50; A61K35/56; A61P35/00; C07D519/00;
- European: C07D515/22; C07D519/00
Application number: EP20070011035 19990405
Priority number(s): EP19990916379 19990405; US19980080802P 19980406
Abstract of EP1876180
The present invention is directed to several newly prepared semi-synthetic ecteinascidin (Et) species, designated herein as Et 757, Boc-Et 729, Iso-Et 743, Et 875, and Et 1560. The physical properties of these compounds, their preparation and bioactivities are also reported.