Treatment of Eye Disorders Characterized by an Elevated Intraocular Pressure by siRNAs
Publication number: US2007270365
Publication date: 2007-11-22
Inventor: JIMENEZ ANA I (ES); SESTO ANGELA (ES); ROMAN JOSE P (ES); GASCON IRENE (ES); GONZALEZ DE BUITRAGO GONZALO (ES)
Applicant: SYLENTIS S A (ES)
Classification:
- international: A61K48/00; A61P27/02; A61K48/00; A61P27/00;
- European: C12N15/11B5; C12N15/11B7
Application number: US20050574169 20050823
Priority number(s): GB20040018762 20040823; GB20050003412 20050218; WO2005GB50134 20050823
Abstract of US2007270365
Sequences and protocols for treatment of eye conditions by use of RNA interference are disclosed. Target genes are selected from those responsible for aqueous flow or aqueous outflow, while particularly preferred conditions to be treated include glaucoma and uveitis.