21 agosto 2012

Ferreres .


Sangre , Clinicas cobran unos 200 euros por bolsa de Sangre ... ¿ Porque no se permite el pago a los Donantes ? .

... Si yo, donante de sangre, descubro que por mi sangre alguien pide dinero, ¿tengo derecho a una parte, a una comisión? Si la sangre es para un familiar enfermo, ¿pueden donársela también otros familiares a coste cero? Una duda más. Desconozco si en la actualidad han cambiado los precios, pero hasta hace dos años el Banc de sang i teixits vendía la bolsa de sangre a hospitales y clínicas privadas a 50 euros la bolsa. Se consideraba un precio simbólico para cubrir los gastos de recogida, equipo técnico y humano. Lo curioso es que posteriormente el cirujano cobraba al paciente 200 euros por bolsa de sangre. Ahora el precio es mayor.

Hace varias décadas, en la posguerra española, se pagaba por donación de sangre en nuestro país y largas colas de gente humilde vendían toda la posible para dar de comer a sus hijos. ¿Volveremos a ver esas colas de la miseria? ¿Se está negociando con la sangre que ofrecemos los donantes?

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Myriad Wins Patent Ruling Again .During fiscal 2012, the company entered into agreements with Pharmamar to conduct companion diagnostic testing for...

With the reaffirmation of an earlier ruling from the U.S. Court of Appeals for the Federal Circuit, a major breakthrough took place for molecular diagnostic company Myriad Genetics, Inc. ( MYGN ). The earlier ruling given on July 29, 2011 confirmed Myriad's right to patent two isolated human genes - BRCA 1 and BRCA 2 - directly related to breast and ovarian cancer. However, the Supreme Court asked for a reconsideration of the whole matter.

The lawsuit was initiated on May 12, 2009 by the Association for Molecular Pathology, et al. (Plaintiffs) in the U.S. District Court for the Southern District of New York with the allegation that Myriad's patents on BRCA 1 and BRCA 2 human genes were invalid and unlawful. Currently, Myriad has exclusive license rights to 525 claims in 24 issued U.S. patents related to Bracanalysis testing.

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We consider Myriad's Bracanalysis system a valuable asset for top-line growth as it has the potential to tap a widely unexplored market. The company considers the oncology market to be huge, with Bracanalysis having penetrated about 50% of the cancer segment. As a result, the favourable second ruling by the U.S. federal appeals court may be considered a positive development for Myriad. The company is currently undertaking various strategies to increase both the market size and penetration level of Bracanalysis. During fiscal 2012, the company entered into agreements with Cephalon, a subsidiary of Teva Pharmaceutical ( TEVA ) and Pharma Mar to conduct companion diagnostic testing for their clinical trials.

RNAI Therapeutics : Are They Back on Big Pharma's Radar Screen? . BUSINESS STRATEGY .

From BioWorld Insight (August 20, 2012) .

... There are a number of early stage clinical trials underway being conducted by biotechnology companies. Tekmira Pharmaceuticals Corp., of Vancouver, for example, has released interim results demonstrating that its RNAi compound TKM-PLK1 in patients with advanced solid tumors is showing promising signs of drug activity in an ongoing Phase I clinical trial. The trial, conducted at oncology centers in the U.S., is an open label, multi-dose, dose escalation study designed to evaluate the safety, tolerability and pharmacokinetics of TKM-PLK1 as well as determine the maximum tolerated dose. Secondary objectives of the trial are to measure tumor response and the pharmacodynamic effects of TKM-PLK1 in patients providing biopsies.

RXi Pharmaceuticals Corp., of Worcester, Mass., has initiated a dose-escalating Phase I trial of its RNAi compound RXI-109, which incorporates self-delivering RNAi technology, for skin scarring following trauma or surgery. And Sylentis SA, of Madrid, Spain, a subsidiary of Grupo Zeltia SA, received authorization from Spanish and Estonian regulatory agencies to begin Phase II trials of RNAi therapeutic SLY040012 for ocular hypertension of glaucoma, looking at efficacy for a range of doses.

Alnylam also has entered several RNAi drugs into clinical trials and is the leading RNAi therapeutic company, said Piper Jaffray analyst Edward A. Tenthoff in a research note. It has initiated a Phase II dose-escalation study of ALN-TTR02 in 20 TTR-amyloidosis patients and plans to begin a pivotal trial in 2013.

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