Martinez-Trufero J, Alfaro J, Felipo F, Alvarez M, Madani J, Cebollero A.Departments of Medical Oncology Pathology , Hospital Universitario Miguel Servet, Zaragoza, Spain.
Meningeal Hemangiopericytoma is an uncommon and aggressive malignancy that, in contrast to meningiomas, shows a high propensity for local recurrence and the development of late extraneural metastases. The results of chemotherapy in advanced hemangiopericytoma have been disappointing, and they have been particularly poor in cases located in the meninges. We report a case of a heavily pretreated metastatic meningeal hemangiopericytoma in which fourth-line chemotherapy with Yondelis ( Trabectedin ) , a Marine-derived Antineoplastic agent effective in treating advanced Soft tissue sarcomas, resulted in clinical benefit.
(C) 2010 Lippincott Williams & Wilkins, Inc.
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