12 abril 2012

Zeltia ends Irvalec trials to focus on core drugs .

... The company will put its cash into further development of Yondelis (trabectedin), which is already approved in Europe for advanced soft tissue sarcoma (STS) and relapsed platinum-sensitive ovarian cancer. It is also in Phase III as a first-line treatment of STS.

Two other key drugs for PharmaMar are Aplidin (plitidepsin), which is in Phase III for multiple myeloma and Phase II for T cell lymphoma, and Zalypsis, which is in Phase II for MM and Ewing's sarcoma. Making up the five compounds are two early-stage antitumour agents PM060184 and PM01183, for which impressive preliminary data have been seen.