24 junio 2021

Resultados de la Fase I-II ApliCov ... La Propia PharmaMar Ya los Público Hace 1 Mes .

 26 Mayo 2021 .

PharmaMar Hace Públicos los Resultados de su Estudio APLICOV-PC en Pacientes Adultos con COVID19 Que Requieren Ingreso Hospitalario.

 Los Datos Obtenidos Han Llevado a la Compañia a Poner en Marcha el Estudio de Fase III NEPTUNO, Que Determinará la Eficacia de Aplidin .


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Estado Actual de la Fase III Neptuno :

Last Verified :June 2021

Studies a U.S. FDA-regulated Drug Product:No
Studies a U.S. FDA-regulated Device ProduceNo

Official Title:A Phase 3, Multicentre, Randomised, Controlled Trial to Determine the Efficacy and Safety of Two Dose Levels of Plitidepsin Versus Control in Adult Patient Requiring Hospitalisation for Management of Moderate COVID-19 Infection
Actual Study Start Date  :June 4, 2021
Estimated Primary Completion Date  :November 2021
Estimated Study Completion Date  :November 2021
Hide 74 study locations
Argentina
Instituto Medico Platense S.A.Not yet recruiting
La Plata, Buenos Aires, Argentina, 1900
Contact: Analia Mykietiuk         
Clinica Privada Monte Grande S.ANot yet recruiting
Monte Grande, Buenos Aires, Argentina, 1842
Contact: Xavier Bocca Ruiz         
Clinica Central S.A.Not yet recruiting
Villa Regina, Rio Negro, Argentina, 8336
Contact: Horacio Ariza         
Sanatorio Parque - RosarioNot yet recruiting
Rosario, Santa Fe, Argentina, 2000
Contact: Luciano Lovesio         
Hospital General Agudos IgnacioNot yet recruiting
Buenos Aires, Argentina, 1428 CABA
Contact: Ricardo Teijerio         
Hospital Francisco MuñizNot yet recruiting
Ciudad autónoma de Buenos Aires, Argentina, C1282AEN CABA
Contact: Rubén Solari         
Hospital RawsonNot yet recruiting
Cordoba, Argentina, 5000
Contact: Lorena Ravera         
Sanatorio Allende CerroNot yet recruiting
Córdoba, Argentina, 5105
Contact: Fernando Riera         
Brazil
Hospital São RafaelNot yet recruiting
Salvador, BA, Brazil, 41253-190
Principal Investigator: Rogerio Passos         
Hospital Moinhos de Vento (HMV)Not yet recruiting
Porto Alegre, RS, Brazil, 90035-001
Contact: Regis Rosa         
Hospital Dia Do PulmãoNot yet recruiting
Blumenau, SC, Brazil, 89030-101
Contact: Marina Lima         
Hospital São JoséNot yet recruiting
Criciuma, SC, Brazil, 88801-250
Contact: Felipe Dal Pizzol (NCI)         
CEMEC - Centro Multidisciplinar de Estudos ClínicosNot yet recruiting
São Bernardo Do Campo, Brazil, 09715-090
Contact: Adilson Calvacante         
Bulgaria
University Multiprofile Hospital for Active Treatment Sveta Ekaterina EADNot yet recruiting
Dimitrovgrad, Bulgaria, 6400
Contact: Todor Atanasov         
Specialized Hospital for Active Treatment of Pneumo-Phthisiatric Diseases - HaskovoNot yet recruiting
Haskovo, Bulgaria, 6300
Contact: Veselin Kalfov         
MHAT "Dr. Nikola Vasiliev" ADNot yet recruiting
Kyustendil, Bulgaria, 2500
Contact: Sashka Pavlova         
Military Medical Academy - MBAL PlevenNot yet recruiting
Pleven, Bulgaria, 5800
Contact: Aneliya Bogdanova         
"Specialised Hospital for Active Treatment for Pneumophthisiatric Diseases Dr. Dimitar Gramatikov - Ruse" Ltd Department of Pneumology and PhthisiatryNot yet recruiting
Ruse, Bulgaria, 7000
Contact: Elena Docheva         
SHATPPD Dr. Dimitar Gramatikov, Ruse Ltd.Not yet recruiting
Ruse, Bulgaria, 7002
Contact: Hristo Metev         
University First MHAT "St.Yoan Krastitel"-Sofia EADNot yet recruiting
Sofia, Bulgaria, 1142
Contact: Dinko Valev         
University Multiprofile Hospital for Active Treatment ACIBADEM CITY CLINIC TOKUDA HOSPIALNot yet recruiting
Sofia, Bulgaria, 1407
Contact: Diana Nikova         
"MHAT "Sveta Anna"" - Sofia ADNot yet recruiting
Sofia, Bulgaria, 1570
Contact: Dimitar Raev         
Colombia
Organización Clinica Bonnadona Prevenir S.A.SNot yet recruiting
Barranquilla, Atlantico, Colombia, 080020
Contact: Jose Navarro         
Clínica de la Costa Ltda.Not yet recruiting
Barranquilla, Atlántico, Colombia, 80020
Contact: Shirley Patricia Iglesias Pertuz         
Hospital Universitario MEDERINot yet recruiting
Bogotá, Bogotá D.C., Colombia, 111911
Contact: Juan Guillermo Lutz         
France
Centre Hospitalier Universitaire (CHU) Dijon Bourgogne - Hopital Francois MitterandNot yet recruiting
Dijon, France, 21079
Contact: Lionel Piroth         
Centre Hospitalier Universitaire de Nantes (CHU de Nantes) - Hotel-DieuNot yet recruiting
Nantes, France, 44000
Contact: François Raffi         
Nouvel Hôpital Civil Service des maladies infectieusesNot yet recruiting
Strasbourg, France, 67091
Contact: Loic Kassagne         
Centre Hospitalier Regional et Universitaire de Tours (CHRU Tours) - Hopital BretonneauNot yet recruiting
Tours, France, 37044
Contact: Louis Bernard (NCI)         
Greece
Democritus University Hospital University General Hospital of AlexandroupolisNot yet recruiting
Alexandroupoli, Greece, 68100
Contact: Periklis Panagopoulos         
Evangelismos Hospital General Hospital of Athens Evangelismos, Intensive Care UnitNot yet recruiting
Athens, Greece, 106 76
Contact: Anastasia Kotanidou         
Sotiria Hospital General Hospital of Chest Diseases of Athens "Sotiria" 3rd Department of Internal Medicine of University of AthensNot yet recruiting
Athens, Greece, 115 27
Contact: Garyfallia Poulakou         
Alexandra HospitalNot yet recruiting
Athens, Greece, 115 28
Contact: Meletios Dimopoulos         
Attikon HospitalNot yet recruiting
Chaïdári, Greece, 12462
Contact: Dimitrios Boumpas         
Tzaneio Hospital General Hospital of Piraeus TzaneioNot yet recruiting
Piraeus, Greece, 185 36
Contact: Styliani Gerakari         
AHEPA Hospital University General Hospital AHEPANot yet recruiting
Thessaloníki, Greece, 54636
Contact: Symeon Metallidis         
Mexico
Hospital Cardiologica AguascalientesNot yet recruiting
Aguascalientes, Ags, Mexico, 20230
Contact: Francisco Marquez Diaz         
Hospital Médica SurNot yet recruiting
Mexico City, Cdmx, Mexico, 14050
Contact: Daniel Antonio Zapata         
Sanatorio Palmore, A.C.Not yet recruiting
Chihuahua, CHH, Mexico, 31020
Contact: Hugo Sánchez         
Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránNot yet recruiting
Mexico City, DIF, Mexico, 14000
Contact: Sergio Ivan Valdes Ferrer         
Centro de Investigación Clínica ChapultepecNot yet recruiting
Morelia, Michoacan, Mexico, 58260
Contact: Guillermo Priciliano Montes Garcia         
Universidad Autonoma de Nuevo Leon - Hospital Universitario "Dr. Jose Eleuterio Gonzalez"Not yet recruiting
Monterrey, NL, Mexico, 64460
Contact: Eduardo Pérez Alba         
Peru
Hospital Alberto Sabogal SologurenNot yet recruiting
Bellavista, Lima, Peru, Callao 2
Contact: Luis Enrique Hercilla Vasquez         
Hospital de ChancayNot yet recruiting
Chancay, Lima, Peru, 15131
Contact: Jose Zambrano         
Contact: Lisbeth Cahuas Villanueva         
Hospital Nacional Hipolito Unanue (HNHU)Not yet recruiting
El Agustino, Lima, Peru, 15007
Contact: Ricardo Sanchez         
Romania
Spitalul Clinic De Boli Infectioase Cluj-Napoca, Sectia HIV/SIDANot yet recruiting
Cluj-Napoca, Cluj, Romania, 400000
Contact: Cristian Jianu         
Spitalul Clinic de Boli Infectioase ConstantaNot yet recruiting
Constanţa, Tomis, Romania, 900709
Contact: Simona Cambrea         
Institutul National De Boli Infectioase "Prof. Dr. Matei Bals"Not yet recruiting
Bucharest, Romania, 021105
Contact: Liliana Lucia Preotescu         
Spitalul Clinic de Boli Infectioase si Tropicale Dr. Victor Babes - BucharestNot yet recruiting
Bucharest, Romania, 030303
Contact: Simin Aysel Florescu         
Institutul National De Boli Infectioase "Prof. Dr. Matei Bals"Not yet recruiting
Bucharest, Romania, 21105
Contact: Anca Streinu-Cercel         
Spitalul Clinic De Boli Infectioase "Sfanta Parascheva" IASI, Sectia Boli Infectioase IIINot yet recruiting
Iaşi, Romania, 700116
Contact: Mihaela Catalina Luca         
Spitalul Judetean de Urgenta 'Sf. Ioan cel Nou' Suceava, Sectia de Boli InfectioaseNot yet recruiting
Suceava, Romania, 720237
Contact: Olga Caliman-Sturdza         
Spain
Hospital Universitari Germans Trias i PujolNot yet recruiting
Badalona, Barcelona, Spain, 08916
Contact: Roger Paredes         
Hospital Universitari de BellvitgeNot yet recruiting
Hospitalet de Llobregat, Barcelona, Spain, 08907
Contact: Maria Molina         
Hospital Universitario HM MontepríncipeRecruiting
Boadilla Del Monte, Madrid, Spain, 28668
Contact: Jose Barberan Lopez         
Hospital Universitario de GetafeNot yet recruiting
Getafe, Madrid, Spain, 28905
Contact: Roberto Vates Gómez         
Hospital Universitario de MóstolesNot yet recruiting
Móstoles, Madrid, Spain, 28935
Contact: Victor Monero Cuerda         
Hospital Quirón MadridNot yet recruiting
Pozuelo De Alarcón, Madrid, Spain, 28223
Contact: Pablo Guisado Vasco         
Contact: Ana Roda         
HM TorrelodonesNot yet recruiting
Torrelodones, Madrid, Spain, 28250
Contact: Mercedes Villarreal         
Hospital Álvaro CunqueiroNot yet recruiting
Vigo, Pontevedra, Spain, 36213
Contact: Maria-Teresa Perez-Rodriguez         
Hospital Universitario de CrucesNot yet recruiting
Barakaldo, Vizcaya, Spain, 48903
Contact: Ane Josune Goikoetxea Agirre         
Hospital General Universitario de AlicanteNot yet recruiting
Alicante, Spain, 3010
Contact: Esperanza Merino         
Hospital Universitario de GuadalajaraNot yet recruiting
Guadalajara, Spain, 19002
Contact: Miguel Torralba         
Hospital Universitari Arnau de Vilanova de LleidaNot yet recruiting
Lleida, Spain, 25198
Contact: Alfredo Jover         
Hospital Infanta LeonorNot yet recruiting
Madrid, Spain, 28032
Contact: Pablo Ryan         
Hospital Universitario Ramón y CajalNot yet recruiting
Madrid, Spain, 28034
Contact: Jesús Fortun-Abete         
Fundacion Jimenez DiazNot yet recruiting
Madrid, Spain, 28040
Contact: Miguel Gorgolas         
Hospital Clínico San CarlosNot yet recruiting
Madrid, Spain, 28040
Contact: Vicente Estrada         
H. HM SanchinarroNot yet recruiting
Madrid, Spain, 28050
Contact: Paula Villares         
Hospital Universitario de SalamancaNot yet recruiting
Salamanca, Spain, 37007
Contact: Miguel Marcos Martin         
Instituto de Investigación Sanitaria Valdecilla (IDIVAL)Not yet recruiting
Santander, Spain, 39008
Contact: Maria Del Carmen Farina Alvarez         
Hospital Universitario Virgen del RocíoRecruiting
Sevilla, Spain, 41013
Contact: Jose Miguel Cisneros         
Contact: Inmaculada Rivas Jeremías         
Turkey
Hacettepe University, School of MedicineNot yet recruiting
Ankara, Turkey, 06100
Contact: Serhat Unal         
Ege University Faculty of Medicine Hospital, Department of Infectious Diseasesaculty of Medicine Hospital, Department of Infectious DiseasesNot yet recruiting
İzmir, Turkey, 35040
Contact: Husnu Pullukcu         
Sponsors and Collaborators
PharmaMar
Investigators
Principal Investigator:José Jimeno Doñaque, MD,