Ewing's Sarcoma Treatment Market; a Need for More Effective and Tolerable Therapies . Pharmamar tiene a Yondelis y Zalypsis en Fase II .

LONDON --(Business Wire)--
The 2010 Ewing's Sarcoma treatments market was valued at $7.4million, according to a new report on companiesandmarkets.com. It is estimated that by 2017 the market will attain a value of $9.4million, representing a growth rate of 3.4% p/a. Growth is restricted by late disease diagnosis and slow increases in levels of incidence.

Ewing's Sarcoma Therapeutics - Pipeline Assessment and Market Forecasts to 2017

http://www.companiesandmarkets.com/Market-Report/ewing-s-sarcoma-therapeutics-pipeline-assessment-and-market-forecasts-to-2017-619814.asp?prk=7c4ed5b510c1ffe12b50d9829eddaba2

The market for Ewing's sarcoma treatments is fairly small, with relatively low levels of incidence compared with other cacers, and represents a distinct opportunity for pharmaceutical companies to expand their profiles. Only one drug is currently approved for treatment - Cosmegen (dactinomycin) - but is no longer in use because of poor efficacy and safety reports.

Other Ewing's sarcoma treatments which are 'off-label' include Vepesid (etoposide); Oncovin (vincristine); Ifex (ifosfamide); Adriamycin (doxorubicin) and Cytoxan/Neosar (cyclophosphamide). All have shown acceptable results, but there is still an unmet need for Ewing's sarcoma therapies which offer safe and effective treatment with new modes of action.

To address this need, pharmaceutical companies have developed several first-in-class molecules for the treatment of Ewing's Sarcoma, such as Yondelis, Zalypsis, sunitinib (Sutent), dasatinib (Sprycel), ganitumab and cixutumumab.

The 69 page report, published in July 2011 report comprises 69 pages of comprehensive evaluation of the Ewing's Sarcoma therapeutic market, including historic and forecast data (2005-2017). Seven major geographies are studied: France, Italy, Germany, Spain, Japan, UK and US. Company profiles are included for Amgen Inc, Eli Lilly and Company and PharmaMar.

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Avastin , el Farmaco más vendido en el Mundo contra en Cancer de Mama ... " No es Eficaz contra el Cancer de Mama " .

Un panel de expertos de la Agencia Estadounidense del Medicamento (la FDA) ha concluido, por unanimidad (6 votos a favor, cero en contra) que el fármaco bevacizumab (más conocido por su nombre comercial Avastin), el medicamento contra el cáncer más vendido en el mundo, no es eficaz para el cáncer de mama.

El organismo ya había mostrado sus dudas sobre la utilidad de Avastin para este tipo de tumores, para el que ofrece poco beneficio en comparación con sus riesgos, y en diciembre ya le impuso restricciones. Sin embargo, ahora se plantea retirar definitivamente esta indicación del prospecto.

La FDA considera que no debe utilizarse para este cáncer, ya que no extiende o mejora la calidad de vida. Sin embargo, a petición de la farmacéutica Roche, fabricante del fármaco, va a tomarse más tiempo para llegar a una conclusión final y ha accedido a escuchar los testimonios de pacientes que afirman que Avastin les ha salvado la vida....