La farmacéutica norteamericana Pfizer podría revolucionar la forma en la que actualmente se realizan los ensayos clínicos, dado que pronto pondrá en marcha una prueba piloto para que las personas que se someten a los mismos puedan hacerlo de forma virtual, sin moverse de sus casas. Esta iniciativa de la multinacional farmacéutica supondría un ahorro de tiempo y dinero para la compañía y facilitaría la colaboración a los pacientes, por lo que sería visto con buenos ojos por las dos partes implicadas.
El método ideado por el departamento de Innovación Clínica de la compañía estaría basado en la introducción de los datos que se requieren a los pacientes en una plataforma de Internet, los cuales pasarían a ser gestionados por el personal científicos para su estudio. "Las personas que se sometan a él solo tendrán que estar familiarizadas con Internet", afirmaba Craig Lipset, responsable de Innovación clínica de Pfizer a una web local de Nueva Jersey.
El experimento anunciado por el laboratorio estadounidense ha levantado ciertas reticencias en parte de la comunidad científica más ortodoxa, que defienden los métodos tradiciones de ensayos clínicos por ofrecer una mayor seguridad y fiabilidad.
24 enero 2012
CimaVax-EGF . La Vacuna Cubana que convierte al cáncer de pulmón en una enfermedad tratable . Esta registrada ya en Cuba y Peru y en proceso en ...
Futuro prometedor para vacuna cubana contra cáncer pulmonarA la vacuna cubana CimaVax-EGF parece esperarle un prometedor 2012. Es el resultado de una investigación de más de 20 años sobre las enfermedades relacionadas con el consumo de tabaco.
Creada por investigadores y científicos en el Centro de Inmunología Molecular (CIM) de La Habana, la vacuna se basa en un principio activo en una proteína que todos tenemos cuando el cáncer no está controlado.
CimaVax-EGF ya ha sido registrada en Perú, y está en proceso de registro en Argentina, Brasil, Colombia y otros países latinoamericanos.
Gisela González, investigadora principal del proyecto, indicó a Radio Nederland que se realizan ensayos clínicos para su registro en Europa y en otros países, como Malasia.
La vacuna hace que el cáncer se convierta en una enfermedad crónica manejable mediante la generación de anticuerpos contra las proteínas que desencadenan la proliferación incontrolada de células.
“Se trata del factor de crecimiento epidérmico que está relacionado con toda la proliferación celular”, nos explica la doctora Gisela González.
Registrada en Cuba desde junio del 2008 y dos meses después en Perú, la vacuna es terapéutica, lo que significa que no es con fines profilácticos, y que convierte al cáncer de pulmón en una enfermedad tratable.
La clave: la EGF
“La EGF es una proteína que se conoce como factor de crecimiento epidérmico, y está relacionada con el crecimiento tumoral. Al vacunar con una combinación que contiene esta proteína, se provoca una respuesta de anticuerpos que reconocen a este factor de crecimiento epidérmico que está en circulación, y se evita que el mismo incida en lo que es la proliferación celular, y por lo tanto en el desarrollo de los tumores sólidos”, nos dice la doctora González.
...
Yondelis / J&J . Zacks Investment Research digest group believe that Johnson & Johnson has a strong pipeline which will accelerate growth in future.
Some firms in the Zacks digest group believe that Johnson & Johnson has a strong pipeline which will accelerate growth in future.Yondelis (Trabectedin).
Indication: Soft Tissue Sarcoma .
Product Life Cycle Status: Phase III .
Partners: The company has a partnership agreement with Spanish biotechnology company, Zeltia, under which Zeltia will market Yondelis in Europe and Japan, while Ortho Biotech will retain the marketing rights for the rest of the world.
... Pagina 13 del Informe de Zacks Investment Research .
J&J 2011 . Fourth-Quarter Sales of $16.3 Billion Increased 3.9%; EPS was $0.08 /./ Full-Year Sales of $65.0 Billion Increased 5.6% .
2011 Fourth-Quarter Sales of $16.3 Billion Increased 3.9%; EPS was $0.08
2011 Full-Year Sales of $65.0 Billion Increased 5.6%; Full-Year EPS was $3.49
Excluding Special Items, 2011 Fourth-Quarter EPS was $1.13, an Increase of 9.7%*
And 2011 Full-Year EPS was $5.00, an Increase of 5.0%*
New Brunswick, NJ (January 24, 2012) - Johnson & Johnson today announced sales of $16.3 billion for the fourth quarter of 2011, an increase of 3.9% as compared to the fourth quarter of 2010. Operational sales increased 4.0% and the negative impact of currency was 0.1%. Domestic sales declined 3.4%, while international sales increased 10.2%, reflecting an operational increase of 10.4% and a negative currency impact of 0.2%. Worldwide sales for the full-year 2011 were $65.0 billion, an increase of 5.6% versus 2010. Operational sales increased 2.8% and the positive impact of currency was 2.8%. Domestic sales declined 1.8%, while international sales increased 12.4%, reflecting operational growth of 7.0% and a positive currency impact of 5.4%.
Net earnings and diluted earnings per share for the fourth quarter of 2011 were $0.2 billion and $0.08, respectively. Fourth-quarter 2011 net earnings reflect after-tax charges of $2.9 billion, which include product liability expenses, the net impact of litigation settlements, costs associated with the DePuy ASR™™ Hip recall program, and an adjustment to the value of a currency option and costs related to the planned acquisition of Synthes, Inc. Fourth-quarter 2010 net earnings included after-tax charges of $922 million representing product liability expenses, the net impact of litigation settlements, and costs associated with the DePuy ASR™ Hip recall program. Excluding these special items for both periods, net earnings for the current quarter were $3.1 billion and diluted earnings per share were $1.13, representing increases of 9.3% and 9.7%, respectively, as compared to the same period in 2010.*
Net earnings and diluted earnings per share for the full-year 2011 were $9.7 billion and $3.49, respectively. Full-year 2011 net earnings reflect after-tax charges of $4.2 billion, which include product liability expenses, the net impact of litigation settlements, a previously announced restructuring charge by Cordis Corporation, costs associated with the DePuy ASR™ Hip recall program, and an adjustment to the value of a currency option and costs related to the planned acquisition of Synthes, Inc. Full-year 2010 net earnings included a net after-tax gain of $55 million representing product liability expenses, the net impact of litigation settlements, and costs associated with the DePuy ASRTMHip recall program. Excluding these special items in both periods, net earnings for the full-year 2011 were $13.9 billion and diluted earnings per share were $5.00, representing increases of 4.4% and 5.0%, respectively, as compared with the full year of 2010.*
The Company announced earnings guidance for full-year 2012 of $5.05 to $5.15 per share, which excludes the impact of special items. This guidance reflects operational growth of approximately 3.5% to 5.5% partially offset by an estimated negative impact of currency of approximately 2.5%.
...
2011 Full-Year Sales of $65.0 Billion Increased 5.6%; Full-Year EPS was $3.49
Excluding Special Items, 2011 Fourth-Quarter EPS was $1.13, an Increase of 9.7%*
And 2011 Full-Year EPS was $5.00, an Increase of 5.0%*
New Brunswick, NJ (January 24, 2012) - Johnson & Johnson today announced sales of $16.3 billion for the fourth quarter of 2011, an increase of 3.9% as compared to the fourth quarter of 2010. Operational sales increased 4.0% and the negative impact of currency was 0.1%. Domestic sales declined 3.4%, while international sales increased 10.2%, reflecting an operational increase of 10.4% and a negative currency impact of 0.2%. Worldwide sales for the full-year 2011 were $65.0 billion, an increase of 5.6% versus 2010. Operational sales increased 2.8% and the positive impact of currency was 2.8%. Domestic sales declined 1.8%, while international sales increased 12.4%, reflecting operational growth of 7.0% and a positive currency impact of 5.4%.
Net earnings and diluted earnings per share for the fourth quarter of 2011 were $0.2 billion and $0.08, respectively. Fourth-quarter 2011 net earnings reflect after-tax charges of $2.9 billion, which include product liability expenses, the net impact of litigation settlements, costs associated with the DePuy ASR™™ Hip recall program, and an adjustment to the value of a currency option and costs related to the planned acquisition of Synthes, Inc. Fourth-quarter 2010 net earnings included after-tax charges of $922 million representing product liability expenses, the net impact of litigation settlements, and costs associated with the DePuy ASR™ Hip recall program. Excluding these special items for both periods, net earnings for the current quarter were $3.1 billion and diluted earnings per share were $1.13, representing increases of 9.3% and 9.7%, respectively, as compared to the same period in 2010.*
Net earnings and diluted earnings per share for the full-year 2011 were $9.7 billion and $3.49, respectively. Full-year 2011 net earnings reflect after-tax charges of $4.2 billion, which include product liability expenses, the net impact of litigation settlements, a previously announced restructuring charge by Cordis Corporation, costs associated with the DePuy ASR™ Hip recall program, and an adjustment to the value of a currency option and costs related to the planned acquisition of Synthes, Inc. Full-year 2010 net earnings included a net after-tax gain of $55 million representing product liability expenses, the net impact of litigation settlements, and costs associated with the DePuy ASRTMHip recall program. Excluding these special items in both periods, net earnings for the full-year 2011 were $13.9 billion and diluted earnings per share were $5.00, representing increases of 4.4% and 5.0%, respectively, as compared with the full year of 2010.*
The Company announced earnings guidance for full-year 2012 of $5.05 to $5.15 per share, which excludes the impact of special items. This guidance reflects operational growth of approximately 3.5% to 5.5% partially offset by an estimated negative impact of currency of approximately 2.5%.
...
Suscribirse a:
Entradas (Atom)