El Instituto de investigación biomédica de Bellvitge (Idibell) participa en un consorcio europeo que fomentará los ensayos clínicos de terapias personalizadas en cáncer de colon, ha informado hoy el centro mediante un comunicado.
El consorcio europeo Coltheres, que cuenta con un presupuesto de 6 millones de euros para los próximos 4 años, está promovido por la Unión Europea y lo integran once instituciones de seis países europeos.
Coltheres, que entró en servicio el pasado 31 de marzo, utilizará los cánceres colorectales como banco de pruebas para definir biomarcadores específicos útiles para el diseño de tratamientos personalizados.
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19 abril 2011
La Fundación Maragall organiza una reunión de expertos en demencia en Boston y presentara alli su Proyecto Cientifico - Asistencial .
La Fundación Pasqual Maragall y la Spain-USA Foundation han organizado una reunión de expertos sobre la demencia el próximo día 27 de abril en Boston para promover una red internacional de contactos entre la entidad creada por Maragall y las instituciones científicas de Estados Unidos.
En este acto, la Fundación Pasqual Maragall, fundada el 2008 para investigar sobre el Alzheimer y las enfermedades neurodegenerativas, presentará su proyecto científico-asistencial ...
En este acto, la Fundación Pasqual Maragall, fundada el 2008 para investigar sobre el Alzheimer y las enfermedades neurodegenerativas, presentará su proyecto científico-asistencial ...
Trabectedin: Safety and Efficacy in the Treatment of Advanced Sarcoma .
Authors: Csaba Gajdos and Anthony Elias . Department of Surgery, GITES Division.
Journal: Clinical Medicine Insights: Oncology .
Abstract
Soft tissue sarcomas (STS) are a rare group of malignancies with multiple different subtypes. Close to half of intermediate or high grade STS develop metastatic disease. Treatment of recurrent/metastatic sarcomas is quite challenging with only a few drugs showing measurable benefits. Trabectedin (ecteinascidin 743, ET-743, Yondelis) is a newly developed alkylating agent that has shown significant broad spectrum potential as a single agent second line drug alone or in combination particularly in the treatment of liposarcomas and leiomyosarcomas. Clinical benefit rates seem to favor its use especially in pretreated patients with recurrent/metastatic disease. The drug is well tolerated in general but hepatotoxicity and hematologic side effects are common. Approved in Europe, the currently ongoing Phase III trials along with the already existing clinical evidence may provide enough data for the Food and Drug Administration for an approval in the US.
Journal: Clinical Medicine Insights: Oncology .
Abstract
Soft tissue sarcomas (STS) are a rare group of malignancies with multiple different subtypes. Close to half of intermediate or high grade STS develop metastatic disease. Treatment of recurrent/metastatic sarcomas is quite challenging with only a few drugs showing measurable benefits. Trabectedin (ecteinascidin 743, ET-743, Yondelis) is a newly developed alkylating agent that has shown significant broad spectrum potential as a single agent second line drug alone or in combination particularly in the treatment of liposarcomas and leiomyosarcomas. Clinical benefit rates seem to favor its use especially in pretreated patients with recurrent/metastatic disease. The drug is well tolerated in general but hepatotoxicity and hematologic side effects are common. Approved in Europe, the currently ongoing Phase III trials along with the already existing clinical evidence may provide enough data for the Food and Drug Administration for an approval in the US.
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