PM01183 . Actualizada Fase II in terms of overall response rate (ORR), in the following advanced solid tumors small cell lung cancer (SCLC), head and neck carcinoma (H&N), neuroendocrine tumors (NETs), biliary tract carcinoma, endometrial carcinoma, carcinoma of unknown primary site, germ cell tumors (GCTs), and Ewing's family of tumors (EFTs) .

Last updated : February 8, 2017 .

Sponsor : PharmaMar

A Multicenter Phase II Clinical Trial of Lurbinectedin (PM01183) in Selected Advanced Solid Tumors to assess the antitumor activity of lurbinectedin (PM01183) in terms of overall response rate (ORR), in the following advanced solid tumors small cell lung cancer (SCLC), head and neck carcinoma (H&N), neuroendocrine tumors (NETs), biliary tract carcinoma, endometrial carcinoma, carcinoma of unknown primary site, germ cell tumors (GCTs), and Ewing's family of tumors (EFTs)

Estimated Enrollment : 250
Study Start Date : August 2015
Estimated Primary Completion Date : July 2019 (Final data collection date for primary outcome measure)

Locations :

UNITED STATES 

United States, California
Sarcoma Oncology Research Center, LLC Recruiting
Santa Monica, California, United States, 90403
Principal Investigator: Sant P. Chawla, MD

United States, Colorado
University of Colorado Cancer Center Recruiting
Aurora, Colorado, United States, 80045
Principal Investigator: Victor Villalobos, MD, PhD

United States, Massachusetts
Dana Farber Cancer Institute Recruiting
Boston, Massachusetts, United States, 02215
Principal Investigator: Geoffrey I. Shapiro, MD, PhD

United States, Texas
The University of Texas MD Anderson Cancer Center Recruiting
Houston, Texas, United States, 77030
Principal Investigator: Vivek Subbiah, MD

Institute for Drug Development, Cancer Therapy & Research Center at University of Texas Health Science Center Recruiting
San Antonio, Texas, United States, 78229
Principal Investigator: John Sarantopoulos, MD

Belgium
Institut Jules Bordet Recruiting
Brussels, Belgium, 1000
Principal Investigator: Ahmad Hussein Awada, MD

France
Hôpital Cochin Recruiting
Paris, France, 75014
Principal Investigator: Jérôme Alexandre, MD
Institut Claudius Regaud Recruiting
Toulouse, France, 31059
Principal Investigator: Jean-Pierre Delord, MD
Institut Gustave Roussy Recruiting
Villejuif, France, 94805
Principal Investigator: Alexandra Leary, MD

Germany
Charité - Universitätsmedizin Berlin Recruiting
Berlin, Germany, 13353
Principal Investigator: Jalid Sehouli, Prof. Dr.
Italy
Istituto Clinico Humanitas Recruiting
Rozzano, Milan, Italy, 20089
Principal Investigator: Armando Santoro, MD
Istituto Ortopedico Rizzoli Recruiting
Bologna, Italy, 40136
Principal Investigator: Stefano Ferrari, MD

Spain
Complexo Hospitalario Universitario de Santiago Recruiting
Santiago de Compostela, A Coruña, Spain, 15706
Principal Investigator: Rafael López López, MD
Hospital Universitario Puerta de Hierro Majadahonda Recruiting
Majadahonda, Madrid, Spain, 28222
Principal Investigator: Mariano Provencio Pulla, MD
Hospital Universitari Vall D' Hebron Recruiting
Barcelona, Spain, 08035
Principal Investigator: Josep María Tabernero, MD
Complejo Hospitalario Regional Reina Sofía Recruiting
Cordoba, Spain, 14004
Principal Investigator: María Jesús Rubio Pérez, MD
Hospital Ramón y Cajal Recruiting
Madrid, Spain, 28034
Principal Investigator: Federico Longo, MD
Hospital Universitario Fundación Jiménez Díaz Recruiting
Madrid, Spain, 28040
Principal Investigator: Víctor Moreno, MD
Hospital Universitario 12 de Octubre Recruiting
Madrid, Spain, 28041
Principal Investigator: Daniel Castellano, MD
Hospital Universitario Madrid Sanchinarro Recruiting
Madrid, Spain, 28050
Principal Investigator: Valentina Boni, MD
Complejo Hospitalario de Especialidades Virgen de la Victoria Recruiting
Malaga, Spain, 29010
Principal Investigator: Jose Manuel Trigo, MD
Hospital Universitari i Polotècnic la Fe Recruiting
Valencia, Spain, 46026
Principal Investigator: Ana Santaballa, MD
Hospital Universitario Miguel Servet Recruiting
Zaragoza, Spain, 50009
Principal Investigator: Antonio Antón, MD

Sweden
Skane University Hospital Recruiting
Lund, Sweden, 22185
Principal Investigator: Anna Sundlöv, MD

Switzerland
Centre Hospitalier Universitaire Vaudois Recruiting
Lausanne, Vaud, Switzerland, 1011
Principal Investigator: Khalil Zaman, Dr

United Kingdom
UCL Cancer Institute Recruiting
London, United Kingdom, WC1E 6DD
Principal Investigator: Rebecca Sophie Kristeleit, Dr

Sponsors and Collaborators
PharmaMar