Publication number: EP2046987 (A2)
Publication date: 2009-04-15
Inventor(s): VILLAHERMOSA JAEN MARIA LUISA [ES]; MORAGA ANA I [ES]
Applicant(s): GENOMICA S A U [ES]
Methods and kits are provided for detection of specific polymorphisms that predispose towards osteoporosis and/or are indicative of likely response to treatment. Particular genes analysed are i) calcitonin Receptor; Vitamin D Receptor; Estrogen Receptor; Collagen I A1; and/or ii) Osteoprotegerin, LRP5, CYP17, CYP19 and MTHFR genes. The two groups may be analysed in separate multiplex amplification reactions on a sample.