Ver en la Pagina 41 del PDF :
Dr. Freedman said that new drugs such as, for example, trabectedin need to be carefully examined in relation to CA-125 modulation because they can modulate the inflammatory component. Macrophage function is the most common inflammatory component associated with ovarian cancer in the peritoneum. What is the relationship of the inflammatory component to CA-125? With the new generation of drugs, there is an opportunity to see the contribution of the inflammatory component to biomarker change. The issue of discordance between CA-125 and objective response needs to be addressed.