2010 , April 28 .Li Y, Giulionatti M, Houghten RA
Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, Florida 34987 and 3550 General Atomics Court, San Diego, California 92121.
The macrolactonization of peptide thioester to yield cyclic depsipeptides was developed using imidazole as a catalyst. This strategy was applied to the synthesis of kahalalide B and its Analogues.
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