04 julio 2016

Yondelis . Es el Anticancerigeno más económico ( Coste Anual ) de los 20 Últimos Anticancerigenos aprobados por la FDA .

These 20 Recently Approved Cancer Drugs Essentially Have 1 Thing in Common .

This has become the new norm for cancer drugs, and neither consumers nor insurers are happy about it.

Cancer Drug Pill Knocking Out Cancer Cell Getty



NEXT-GENERATION CANCER DRUGS OFFER NEW HOPE TO PATIENTS. IMAGE SOURCE: GETTY IMAGES.






U.S. Food and Drug Administration has been a busy bee of late. Even though the drug development process of taking a molecule from discovery to the pharmacy shelf can take upwards of a decade, the FDA has approved 73 novel drugs since September 2014. Of these 73 new drugs, a whopping 20 of them are targeting cancer.

It's not hard to understand why oncology is such a hot area of research for drug developers. According to the IMS Institute for Healthcare Informatics' annual Global Oncology Trend Report, cancer-drug sales totaled $107 billion in 2015, and they're expected to climb to $150 billion by 2020. Cancer, itself, is a large unmet disease, giving both big and small players an opportunity to make a difference, as well as fund future research with the potential profits of approved drugs.

New cancer drugs are all extremely pricey
But the one factor that really stands out regarding the 20 cancer drugs approved since September 2014 is that they're essentially all extremely expensive for both the consumer and insurance companies. Here are the approximate annual costs of these 20 cancer drugs, listed in chronological order with the most recent approval first.


These 20 Recently Approved Cancer Drugs Essentially Have 1 Thing in Common
This has become the new norm for cancer drugs, and neither consumers nor insurers are happy about it.

Cancer Drug Pill Knocking Out Cancer Cell Getty


NEXT-GENERATION CANCER DRUGS OFFER NEW HOPE TO PATIENTS. IMAGE SOURCE: GETTY IMAGES. 


The U.S. Food and Drug Administration has been a busy bee of late. Even though the drug development process of taking a molecule from discovery to the pharmacy shelf can take upwards of a decade, the FDA has approved 73 novel drugs since September 2014. Of these 73 new drugs, a whopping 20 of them are targeting cancer.


It's not hard to understand why oncology is such a hot area of research for drug developers. According to the IMS Institute for Healthcare Informatics' annual Global Oncology Trend Report, cancer-drug sales totaled $107 billion in 2015, and they're expected to climb to $150 billion by 2020. Cancer, itself, is a large unmet disease, giving both big and small players an opportunity to make a difference, as well as fund future research with the potential profits of approved drugs.


New cancer drugs are all extremely pricey
But the one factor that really stands out regarding the 20 cancer drugs approved since September 2014 is that they're essentially all extremely expensive for both the consumer and insurance companies. Here are the approximate annual costs of these 20 cancer drugs, listed in chronological order with the most recent approval first.



Drug
Approximate Annual Cost
Tecentriq
$150,000
Venclexta
$109,500
Alacensa
$150,000
Empliciti
$142,000
Portrazza
$173,200
Ninlaro
$104,000
Darzalex
$135,000
Tagrisso
$153,000
Cotellic (w/Zelboraf)
$211,200
Yondelis
$40,500
Lonsurf
Insufficient data
Odomzo
$144,000
Unituxin
$150,000
Farydak
$109,800
Lenvima
$167,300
Ibrance
$118,200
Opdivo
$143,000
Lynparza
Insufficient data
Blincyto
$178,000
Keytruda
$150,000



TABLE BY AUTHOR. DATA FROM VARIOUS NEWS SOURCES. LONSURF AND LYNPARZA DID NOT HAVE RELIABLE U.S. COST DATA, AND THUS ARE REPRESENTED AS "INSUFFICIENT DATA." .

With the exception of Yondelis, a chemotherapy treatment administered to treat soft tissue sarcomas, there isn't a single cancer drug approved since September 2014 that costs less than $104,000 annually at the wholesale level. Understand that insurers are almost assuredly getting some level of gross-to-net discounts from these drugmakers off wholesale listed prices, and that patients taking these drugs may not be on them for an entire year. Life expectancies and treatment tolerability vary by cancer type and the drug being administered, so in some cases these drug costs may be more palatable than what you see above.

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PharmaMar según Gescooperativo : The Company’s Pipeline has Potential, it is shortly to be listed on the Nasdaq (which we think could help reduce the stock’s volatility) and its share price has dropped over 60% since the end of last year. These are all reasons why we have increased our exposure to the company.

Spain’s Small, Midcaps Weather The Brexit Storm Better .


 Fernando Rodriguez .



 Los S&M Cap Españoles soportan el 'Brexit' mejor que los grandes valores.




Los Gestores de Santander, Bankia y Gescooperativo explican sus estrategias a Consenso del Mercado.

“Con carácter general creemos que la exposición de estas compañías al 'Brexit' es limitada por la reducida exposición de las ventas a Reino Unido. Por lo tanto, no se van a ver tan afectadas, como se puso de manifiesto el día después del 'Brexit', cuando el Ibex-35 retrocedió el 12,35% y las caídas fueron más limitadas para el Ibex Small Cap (8,08%) y el Ibex Medium Cap (7,49%)”, explica Beatriz Gutiérrez, subdirectora de Gescooperativo, la gestora de inversión colectiva del Grupo Cajas Rurales, que invierte en S&M Cap españoles a través de dos fondos: Rural Pequeñas Compañías Iberia FI y Gescooperativo Small Caps Euro.

... En lo que respecta al fondo Rural Pequeñas Compañías Iberia, gestionado por Gescooperativo, la estrategia inversora es “encontrar buenos negocios (con alta rentabilidad sobre el capital empleado), a buen precio, bien gestionados y con balances solventes”.
PharmaMar es uno de los 3 valores que más pesan en el fondo Rural Pequeñas Compañías Iberia : Un Pipeline (es decir, una cartera de productos en maduración) con potencial, la inminente salida a cotización en el Nasdaq (que creemos que podría ayudar a reducir la volatilidad del valor) y una caída en la cotización de más del 60% desde finales del año pasado, nos han llevado a incrementar la exposición en la compañía.
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