Synthetic methods for aplidine and new antitumoral derivatives, methods of making and using them .
Publication number: US2008009435
Publication date: 2008-01-10
Inventor: RODRIGUEZ IGNACIO (ES); POLANCO CONCEPCION (ES); CUEVAS FELIX (ES); MENDEZ PALOMA (ES); CUEVAS CARMEN (ES); GALLEGO PILAR (ES); MUNT SIMON (ES); MANZANARES IGNACIO (ES)
Applicant: PHARMA MAR S A A SPAIN CORP
Classification:
- international: A61K38/00; A61K38/12; A61P35/00; C07K1/06; C07K5/02; C07K5/083; C07K7/02; C07K11/00; C07K11/02; A61K38/00; A61K38/12; A61P35/00; C07K1/00; C07K5/00; C07K7/00; C07K11/00;
- European: C07K5/02B; C07K5/08A1B; C07K7/02
Application number: US20070788866 20070420
Priority number(s): US20070788866 20070420; GB20000016148 20000630; GB20010003750 20010215; US20030312341 20030728; WO2001GB02901 20010702
Abstract of US2008009435
The invention relates to aplidine derivatives of the general formula: which are useful for the treatment of tumors.