Se trata de una Patente que ya se consiguio en el 2003 y que se va ampliando .... se trata de los hermanos del ET-743 y son el Et-770 or Et-729 are provided. The derivatives are of the general formula (Ia) wherein the substituent groups take various permitted meanings.
Antitumoral derivatives of Ecteinascidin ET-743
Publication number: EP1854800
Publication date: 2007-11-14
Inventor: MARTINEZ VALENTIN (ES); FLORES MARIA (ES); GALLEGO PILAR (ES); CUEVAS CARMEN (ES); MUNT SIMON (ES); MANZANARES IGNACIO (ES)
Applicant: PHARMA MAR SA (ES)
Classification:
- international: C07D515/22; A61K31/495; A61K31/4995; A61P35/00; C07D515/00; A61K31/495; A61K31/4995; A61P35/00;
- European: C07D515/22
Application number: EP20070011446 20020717
Priority number(s): EP20020747577 20020717; GB20010017402 20010717