CAR T Cells Push Forward in Solid Tumors Following Positive Results in Hematology .

Chimeric antigen receptor (CAR) T-cell therapy continues to evolve through research for the treatment of patients with hematologic malignancies. In particular, cellular therapy has appeared most promising for the treatment of lymphomas and leukemias, in which the FDA has already approved several indications for CAR T cells.

As researchers continue to be impressed with responses observed with cellular therapy, there is a greater interest in moving CAR T-cell therapy into the treatment landscape for patients with solid tumors. However, there are a number of challenges with using CAR T cells in this patient population, such as the different tumor microenvironments of the disease.