MedwireNews:
Lurbinectedin, a selective inhibitor of active transcription of protein-coding genes, has promising activity in patients with BRCA1/2-mutated metastatic breast cancer, phase II study data show.
The efficacy was particularly good in women with BRCA2 mutations suggesting that “[a]dditional clinical development in this subset of patients […] is warranted,” Judith Balamaña (Vall d’Hebron Institute of Oncology, Barcelona, Spain) and co-investigators remark.
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