Thapsigargin . Scientists Uncover Potential Antiviral Treatment For COVID-19 . "" Esta Aún en las Primeras Etapas de la Investigación "" . *** No Consta Ensayo Clínico Alguno ... Ni de Preclinica *** .

 Scientists Uncover Potential Antiviral Treatment for COVID-19.

UNIVERSITY OF NOTTINGHAM , 2 February 2021 .

Researchers from the University of Nottingham have discovered a novel antiviral property of a drug that could have major implications in how future epidemics / pandemics - including Covid-19 - are managed.

The study, published in Viruses*, shows that thapsigargin is a promising broad spectrum antiviral, highly effective against Covid-19 virus (SARS-CoV-2), a common cold coronavirus, respiratory syncytial virus (RSV) and the influenza A virus.

Given that acute respiratory virus infections caused by different viruses are clinically indistinguishable on presentation, an effective broad-spectrum that can target different virus types at the same time could significantly improve clinical management. An antiviral of this type could potentially be made available for community use to control active infection and its spread.

The study is a collaborative project led by Professor Kin-Chow Chang and experts at the University of Nottingham (Schools of Veterinary Medicine and Sciences, Biosciences, Pharmacy, Medicine, and Chemistry), and colleagues at the Animal and Plant Health Agency (APHA), China Agricultural University and the Pirbright Institute.

In this ground-breaking study, the team of experts found that the plant-derived antiviral, at small doses, triggers a highly effective broad-spectrum host-centred antiviral innate immune response against three major types of human respiratory viruses - including Covid-19. ...